Slide screening test for glandular fever.

نویسندگان

  • W BRUMFITT
  • F O'GRADY
چکیده

The modification of Paul and Bunnell's (1932) original haemagglutination test for glandular fever described by Davidsohn (1937) which is used in its original or further modified forms in most laboratories, while simple to perform, is time consuming both in execution and in the delay before reading. Butt and Foord (1935) had claimed that, if sera which showed a positive Paul-Bunnell titre were mixed with sheep cells in a hanging drop preparation, agglutination was inumediate. Following this observation, Straus (1936) developed rapid slide and tube tests. Similar slide screening tests have been used with considerable success by Rappaport and Skariton (1949), Moloney and Malzone (1949), and Vaughn (1951), the number of false results either negative or positive being small or absent in their experience. In these reports, however, the majority ofpatients were definitely not suffering from glandular fever. It appeared of interest, therefore, to compare the results of the very simple test described by Vaughn with the conventional Davidsohn absorption technique in the circumstances in which the test is most commonly applied in practice, that is, in a series of cases in which the clinical diagnosis was glandular fever. The results in both the serologically confirmed and unconfirmed cases are included.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 10 3  شماره 

صفحات  -

تاریخ انتشار 1957